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ANTHEPROT - Signal
prediction
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The solvent accessiblity method (von Heijne, 1998) is useful to predict
the location of :
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Potential signal peptide
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Prediction of cleavage site
Principle
The parameters of the methods are taken from the database of signal
peptides. The occurence of amino acids at each position of a signal peptide
was calculated for eucaryotic and procaryotic sequences separately. Then
a frequency table was established and used to calculate the score o all
windows (15 aa long) moving along the actual sequence. The most probable
cleavage site was the highest score obtained.
Result
How to make it with ANTHEPROT?
Since, you need only 1 sequence, the signal prediction can be obtained
when only one sequence is loaded.